Grand Rounds Prompt: Diagnosing Pancreatic Cancer Earlier

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Question: "What are the most promising strategies for improving the early detection of pancreatic cancer in 2024 and beyond? Specifically, how can AI-powered radiomics, molecular markers (e.g., KRAS mutations), and liquid biopsy techniques be integrated into clinical practice to identify high-risk patients? Additionally, discuss the role of family history, germline genetic testing, and AI-driven decision support in creating personalized surveillance programs. How do these innovations impact patient outcomes, and what are the challenges in their widespread adoption?"